By Michael Palmer

An built-in method of the research of drug motion mechanisms

Biochemical Pharmacology is a concise and modern textbook at the ideas of drug motion. It discusses consultant medications via instance to discover the diversity of biochemical ambitions and mechanisms. The ebook explains a number of the experiments that let us know how medications paintings, and it outlines the physiological and pathological context that make these motion mechanisms therapeutically useful.

Biochemical Pharmacology is meant essentially for college kids in biology and biochemistry on the complicated undergraduate or graduate degrees. For lecture room use, the illustrations from the booklet are individually to be had as PowerPoint slides. it really is written in a conversational, shiny variety that quite simply encourages scholars to discover this significant region of scientific technological know-how. Biochemical Pharmacology may also function an advent for execs in biosciences, in addition to in pharmaceutical and wellbeing and fitness sciences.

Complete with a number of figures in the course of the textual content, that are additionally to be had individually as PowerPoint slides, Biochemical Pharmacology:

  • Explains the function of pharmacodynamics, pharmacokinetics, and drug metabolism in drug action

  • Provides consultant examples from the pharmacology of mobilephone excitation, hormones, nitric oxide, chemotherapy, and others

  • Examines rising purposes of ribonucleic acids as medicinal drugs and drug targets

  • Discusses what researchers want to know in regards to the difficulties of drug distribution, removing, and toxicity

Biochemical Pharmacology is a crucial source for someone wishing to realize an in-depth realizing of drug motion mechanisms and very worthy for researchers wishing to discover a few of the unanswered questions .

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Released concurrently in Canada. No a part of this booklet can be reproduced, kept in a retrieval method or transmitted in any shape or whatsoever, digital, mechanical, photocopying, recording, scanning or in a different way, other than as approved below part 107 or 108 of the 1976 usa Copyright Act, with out both the earlier written permission of the writer, or authorization via cost of the precise per-copy cost to the Copyright Clearance heart, Inc. , 222 Rosewood force, Danvers, MA 01923, (978) 750-8400, fax (978) 750-4470, or on the net at www. copyright. com. Requests to the writer for permission can be addressed to the Permissions division, John Wiley & Sons, Inc. , 111 River road, Hoboken, NJ 07030, (201) 748-6011, fax (201) 748-6008, or on-line at http://www. wiley. com/go/permission. restrict of Liability/Disclaimer of guaranty: whereas the writer and writer have used their top efforts in getting ready this publication, they make no illustration or warranties with recognize to the accuracy or completeness of the contents of this ebook and in particular disclaim any implied warranties of merchantability or health for a specific objective. No guaranty might be created or prolonged through revenues representatives or written revenues fabrics. the recommendation and methods contained herein is probably not appropriate on your state of affairs. you want to seek advice from a certified the place applicable. Neither the writer nor writer will probably be responsible for any lack of revenue or the other advertisement damages, together with yet no longer constrained to big, incidental, consequential, or different damages. For common info on our different services please touch our purchaser Care division in the usa at (800) 762-2974, outdoor the us at (317) 572-3993 or fax (317) 572-4002. Wiley additionally publishes its books in numerous digital codecs. a few content material that looks in print, even though, is probably not on hand in digital codecs. for additional info approximately Wiley items, stopover at our website at www. wiley. com. Library of Congress Cataloging-in-Publication info: Palmer, Michael, 1961 may possibly four Biochemical pharmacology / Michael Palmer; with chapters through Alice Chan, Thorsten Dieckmann, John Honek. — lsted. p. ; cm. contains bibliographical references and index. ISBN 978-0-470-17445-6 (hardback) I. name. [DNLM: 1. Drug Interactions. 2. Pharmacokinetics. three. Drug supply structures. four. Pharmaceutical arrangements. QV38] 615. 7045—dc23 published within the u . s .. 10 nine eight 7 6 five four three 2 1 2011041617 CONTENTS Preface ix Acknowledgments xi 1 2 advent 1. 1 1. 2 1. three starting place and practise of gear medicinal drugs and drug ambitions Drug molecules may possibly or won't resemble the physiological ligands in their receptors 1. four options of drug discovery and improvement References Pharmacodynamics 2. 1 Molecular positive aspects of drug-receptor interplay 2. 2 idea of drug-receptor binding 2. three Dose-effect relationships in signaling cascades 2. four efficiency and efficacy 2. five useful and poisonous drug results 2.

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